Zhou Yayi started learning the Guzheng at a very young age. At the age of 6, she started learning the Guzheng from Lu Jing, professor at Sichuan Conservatory of Music Middle school. In 2009, Yayi successfully entered the Sichuan Conservatory of Music Middle school. Then, she was under the tutelage of Lu Jing, Jiang Zhanxi and Zhang Yin, from Sichuan Conservatory Middle school and Chengdu Modern Chamber Orchestra respectively. Then in 2015, Zhou Yayi entered Nanyang Academy of Fine Arts Singapore (NAFA) and began being under the tutelage of Singapore Chinese Orchestra Guzheng Musician, Xu Hui.